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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
23.94
Human Site:
T471
Identified Species:
40.51
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
T471
K
K
G
I
L
K
K
T
Q
Q
R
E
S
G
Y
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
T471
K
K
G
I
L
K
K
T
Q
Q
R
E
S
G
Y
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
T477
K
K
G
I
L
K
K
T
Q
Q
R
E
S
G
Y
Dog
Lupus familis
XP_538417
666
74288
T476
K
K
G
I
L
K
K
T
Q
Q
R
E
S
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
T472
K
K
G
I
L
K
K
T
Q
Q
R
E
S
G
Y
Rat
Rattus norvegicus
Q66HE5
630
69934
L450
P
V
P
A
I
P
L
L
P
R
K
G
I
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
T471
K
K
G
I
L
K
K
T
Q
Q
R
E
S
G
Y
Chicken
Gallus gallus
Q9IA88
798
88848
P463
E
I
K
A
Y
D
H
P
I
R
I
P
S
N
T
Frog
Xenopus laevis
NP_001088596
570
64876
D390
S
S
P
E
H
N
E
D
Q
T
Q
T
Q
N
N
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
V793
Q
Q
Q
V
T
I
Q
V
Q
E
V
E
L
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
M1094
A
M
R
F
S
T
E
M
Q
H
P
V
A
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
I637
P
S
S
N
T
T
Q
I
A
Q
I
P
P
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
L331
A
T
V
T
Y
Y
L
L
L
D
N
R
F
R
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
T450
S
A
I
T
Q
Q
R
T
Y
H
Q
S
P
F
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
6.6
6.6
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
20
20
53.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
15
0
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
8
0
0
0
8
0
% D
% Glu:
8
0
0
8
0
0
15
0
0
8
0
50
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
8
% F
% Gly:
0
0
43
0
0
0
0
0
0
0
0
8
0
50
8
% G
% His:
0
0
0
0
8
0
8
0
0
15
0
0
0
0
0
% H
% Ile:
0
8
8
43
8
8
0
8
8
0
15
0
8
0
0
% I
% Lys:
43
43
8
0
0
43
43
0
0
0
8
0
0
0
8
% K
% Leu:
0
0
0
0
43
0
15
15
8
0
0
0
8
15
8
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
8
0
0
15
8
% N
% Pro:
15
0
15
0
0
8
0
8
8
0
8
15
15
0
0
% P
% Gln:
8
8
8
0
8
8
15
0
65
50
15
0
8
0
0
% Q
% Arg:
0
0
8
0
0
0
8
0
0
15
43
8
0
8
0
% R
% Ser:
15
15
8
0
8
0
0
0
0
0
0
8
50
0
0
% S
% Thr:
0
8
0
15
15
15
0
50
0
8
0
8
0
0
8
% T
% Val:
0
8
8
8
0
0
0
8
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
8
0
0
8
0
0
0
0
0
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _